1977

Oen, EO

Nord. VetMed. 

10 mg/month (contraception)

​

1977

Houdeshell, JW and Hennessey, PW

Megestrol acetate for control of estrus in the cat

Vet. Med. Small Anim. Clin.

10 mg/month (contraception)

​

1981

Gosselin, Y, et al.

The use of megestrol acetate in some feline dermatological problems

Can. Vet. J. 

70 mg/1st month of treatment (eosinophilic ulcer, endocrine alopecia, miliary dermatitis)

​

​

two studies

60-80 mg/1st month of treatment (to halt urinary spraying)

​

Kern, Thomas J.

Diseases of the Cornea and Sclera

Saunders Manual of Small Animal Practice

17.75 mg or more/1st month of treatment

​

2015

Romagnoli, Stefano

Progestins to Control Feline Reproduction: Historical Abuse of High Doses and potentially safe use      of low doses

J. Feline Med. Surg. 

​                                                                               

COMPARE PAST DOSES

- LOW   10 mg /month                                                    

- MED   17.5 mg/wk for 1-2 wks or     

               35 mg/month for mos/yrs              

- HIGH  40-80 mg/month 1+ yr

                       

THE MINI-DOSE NEEDED TO PREVENT

PREGNANCY IN A CAT IS 0.5 mg/wk (2 mg/month)

 

2022

Romagnoli, Stefano and Lluis Ferre'-Dolcet

J. Fel. Med. and Surg.

 

"Contrary to published misinformation, the queen's reproductive cycle can be temporarily and reversibly blocked using progestens without any tangible consequence  for future health and fertility."

  

                                                                                                                                   

​